A guard now stand outside the doors of the cafe to prevent users from entering and to stop them harassing customers enjoying a drink at tables in front of the branch.
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A Caffè Nero spokesperson said: “This area is known for its anti-social behaviour.
“Some of our team members there have suffered both verbal and physical abuse as a result, which is wholly unacceptable.
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“They are very often young women and we simply cannot tolerate them being put into these situations.
“Their safety and well-being is our absolute priority.”
The move comes as a Spice addict was today banned from the city centre for two years for openly smoking drugs, abusing members of the public and shop workers as well as aggressively begging.
At a Manchester Civil Justice Centre hearing rough sleeper Priestley Cleworth, 24, was told he faces jail if he breaches the order.
